FACTS ABOUT LDN-27219 PRECLINICAL RESEARCH REVEALED

A single especially interesting compound is LDN-27219. When most tTG inhibitors are intended to bind for the protein crosslinking Lively internet site, LDN-27219 as an alternative binds towards the nucleotide binding pocket of the enzyme even though it's in its shut-point out conformation, and stabilizes that conformation to avoid crosslinking acti